The rescuing and nursing of 3 ectopic pregnancy patients suffering from severe toxicity of low-dose methotrexate treatment
10.3761/j.issn.0254-1769.2025.06.016
- VernacularTitle:3例小剂量甲氨蝶呤治疗异位妊娠致严重毒性反应的解救与护理
- Author:
Xiaoyuan ZHANG
1
;
Huifeng LU
;
Na YU
;
Yuying YAN
;
Yu WANG
;
Li XIE
Author Information
1. 310006 杭州市 浙江大学医学院附属妇产科医院妇三科
- Publication Type:Journal Article
- Keywords:
Methotrexate;
Ectopic Pregnancy;
Myelosuppression;
Toxicity Reaction;
Obstetrical Nursing
- From:
Chinese Journal of Nursing
2025;60(6):743-748
- CountryChina
- Language:Chinese
-
Abstract:
To summarize rescuing and nursing experience of 3 ectopic pregnancy patients,suffering from severe toxicity caused by low-dose methotrexate(MTX)treatment.The key points include:constantly monitoring of patients for at least a week after MTX administration,and identifying MTX toxicity related symptoms as soon as possible;promptly establishing a multidisciplinary medical team to establish individualized rescue plans;quickly initiating the rescue therapy and implementing targeted fluid management to accelerate MTX excretion;intensifying protective isolation caring to prevent and control infection;applying refined safety management to prevent spontaneous bleeding;providing intensive caring of skin and mucosal toxicity symptoms to promote healing process;supplying individualized psychological counseling and support in time;strengthening the protection of the damaged organ.After emergent rescuing and intensive nursing,all 3 patients successfully recovered and were discharged from the hospital.
