Analysis of the Disease Burden of Lung Cancer Attributable to Air Pollution in China from 1990 to 2021
10.11783/j.issn.1002-3674.2025.03.006
- VernacularTitle:1990-2021年中国归因于空气污染的肺癌疾病负担分析
- Author:
Yueyi LIU
1
;
Zhenling CUI
1
Author Information
1. 中国农业大学资源与环境学院(100193)
- Publication Type:Journal Article
- Keywords:
Lung cancer;
Air pollution;
Disease burden;
Joinpoint regression model;
Age-period-cohort model
- From:
Chinese Journal of Health Statistics
2025;42(3):350-354
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the disease burden of lung cancer attributable to air pollution among the Chinese population from 1990 to 2021,providing a scientific basis for the prevention and control strategies of lung cancer.Methods Data on deaths,mortality rates,disability-adjusted life years(DALY)of lung cancer,and world population data attributable to air pollution in China from 1990 to 2021 were extracted from the global burden of disease study 2021(GBD 2021).The Joinpoint regression model was used to calculate the annual percentage change(APC)and average annual percentage change(AAPC)for analysis of disease burden.The age-period-cohort model was employed to investigate the effects of age,period,and cohort on the trends in lung cancer disease burden attributable to air pollution.Results The population attributable fraction(PAF)of lung cancer in China due to air pollution has shown a trend of decrease,with an average AAPC value of-1.16%(P<0.001).The numbers of death and DALYs generally increased by years,with an AAPC value of 2.14%and 1.54%,respectively(both P<0.001).However,the standardized mortality rate and standardized DALY rate initially increased and then decreased,with an AAPC value of 0.34%and-0.14%,respectively,showing no statistical significance.The mortality rate,standardized mortality rate,DALY rate,and standardized DALY rate of lung cancer attributable to air pollution were higher in males than in females.Age-period-cohort model analysis showed that the net drifts of lung cancer mortality rates attributable to air pollution for the overall population,males,and females were-1.52%,-1.33%,and-1.88%,respectively(all P<0.001).The death risk increased with age.There are higher mortality rates in males across all age groups compared to females,especially in the population over 50 years.The period effect showed a U-shape trend from 1990 to 2004,and a decreasing trend after 2005.There was a decreasing trend of death risk with the progression of birth cohorts.Conclusion From 1990 to 2021,the relative contribution of air pollution to lung cancer in China has gradually decreased,and the risk of lung cancer death attributable to air pollution has generally shown a downward trend.The risk is higher in males than in females,higher in elderly population,and lower with the progression of birth cohorts.Increased attention should be paid to high-risk groups such as males and the elderly population,and early screening and intervention for the disease should be strengthened to reduce the risk of lung cancer.
