Current status and prospects for screening early-stage hepatocellular carcinoma

VernacularTitle:肝细胞癌早期筛查现状及展望
Author: Haolin SONG ¹ ; Shoufeng JIANG ; Xue YANG ; Xiaoxiao YAO ; Chenwei PAN ; Ping CHEN
Author Information

1. 浙江大学医学院，杭州　310027
Publication Type:Journal Article
Keywords: Hepatocellular carcinoma; Screening; Diagnosis; Liquid biopsy
From: Chinese Journal of Hepatology 2025;33(1):70-76
CountryChina
Language:Chinese
Abstract: Hepatocellular carcinoma is the most common type of primary liver cancer. Many patients who have been diagnosed with hepatocellular carcinoma are already at an advanced stage, leading to very limited treatment options and poor prognosis. Therefore, the key to improving prognosis is early-stage diagnosis. In recent years, with deeper analysis of the underlying biological mechanisms of HCC, new diagnostic methods have emerged, including emerging serum markers, liquid biopsy, molecular diagnostics, and imaging techniques. This article reviews and analyzes the research progress on early-stage screening and explores their value and application prospects in the early predictive diagnosis of HCC..