Study on the relationship between PLR and the prognosis of acute respiratory distress syndrome
10.3969/j.issn.1673-9701.2025.09.002
- VernacularTitle:PLR与急性呼吸窘迫综合征预后关系研究
- Author:
Rujie CHEN
1
;
Wangfeng ZHOU
1
;
Xianyang GUO
1
Author Information
1. 温州医科大学附属第二医院重症医学科,浙江温州 325027
- Publication Type:Journal Article
- Keywords:
Platelet-to-lymphocyte ratio;
Acute respiratory distress syndrome;
Logistic regression analysis;
Prognosis;
ARDS grading
- From:
China Modern Doctor
2025;63(9):5-8
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between platelet-to-lymphocyte ratio(PLR)and the prognosis of actue respiratory distress syndrome(ARDS).Methods A total of 182 patients with ARDS admitted to the Second Affiliated Hospital of Wenzhou Medical College from January 2015 to September 2024 were included,including 98 cases in treatment improvement group and 84 cases in death group.The relevant factors included gender,age,height,body mass,body mass index(BMI),nutritional risk screening scores 2002(NRS2002),diabetes,hypertension,procalcitoinn(PCT),ARDS grading(mild-moderate/severe),acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)scores,PLR and whether to use vasopressor drugs between two groups were recorded and compared.The related factors of ARDS prognosis were evaluated by univariate factor Logistical regression analysis,and the statistical significant variables were analyzed by multivariate factor Logistical regression analysis.Results Univariate Logistic regression analysis showed that height,body mass,gender,hypertension,diabetes,PCT and NRS2002 were not significantly related to the prognosis of patients with ARDS(P＞0.05);Age,BMI,APACHE Ⅱ score,PLR,whether to use vasopressor drugs and ARDS grading are closely related to the prognosis of ARDS patients(P＜0.05).By multivariate factor Logistical regression analysis for closely related factor,PLR(OR=1.113,95％CI:1.047-1.278),APACHE Ⅱ scores(OR=1.279,95％CI:1.110-1.473)and ARDS grading(OR=3.769,95％CI:1.397-10.167)were independent risk factors of ARDS prognosis.Conclusion PLR,APACHE Ⅱ scores and ARDS grading were closely related to the prognosis of ARDS.
