Risk factors of complications in facial autologous fat transplantation
10.3760/cma.j.cn114657-20241206-00208
- VernacularTitle:面部自体脂肪移植术后发生并发症的影响因素分析
- Author:
Qian WU
1
;
Haina PEI
;
Guiwen ZHOU
;
Qiang FU
;
Ruiqi BAI
;
Peixuan ZHANG
;
Minliang CHEN
Author Information
1. 中国医学科学院 北京协和医学院 整形外科医院创伤修复与组织再生科，北京 100144
- Publication Type:Journal Article
- Keywords:
Adipose tissue;
Fat transplantation;
Complications;
Risk factors
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2025;31(5):496-501
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the risk factors for complications of facial autologous fat transplantation.Methods:A total of 51 female patients (case group) with moderate to severe complications following facial autologous fat transplantation at the Fourth Medical Center of Chinese PLA General Hospital from November 2016 to October 2022 were included in this retrospective study. The median age was 31.0 (27.0, 40.0) years. After age and surgical date were matched with ratio of 1∶1, a total of 51 female patients who received autologous fat transplants at several official medical facilities and experienced no complications within a year after the procedure made up the control group. The median age of the control group was 32.0 (26.0, 41.0) years. The clinical characteristics of the two groups were compared, and the factors for complications of facial autologous fat transplantation were examined using a multivariate logistic regression model.Results:In the case group, complications included facial artery embolism (7 cases), ophthalmic artery embolism (19 cases), infection (19 cases), and fat necrosis (6 cases), with 26 severe and 25 moderate cases. No significant differences were found between the two groups in age, body mass index (BMI), marital status, history of hypertension, infectious diseases, allergies, smoking, or alcohol consumption (all P>0.05). However, significant differences were observed in a history of facial surgery, perimenstrual phase, surgical site, and fat donor site (all P<0.05). Multivariate logistic regression analysis revealed that a history of facial surgery ( OR=17.289, 95% CI: 4.851-61.616, P<0.001) and the surgical site being a clinic/outpatient department (compared to a hospital, OR=7.708, 95% CI: 2.482-23.939, P<0.001) were risk factors for postoperative complications after facial autologous fat transplantation. Conclusion:A history of facial surgery and the surgical site being a clinic/outpatient department (compared to a hospital) are risk factors for complications of facial autologous fat transplantation.
