Effect and safety of water-light injection combined with concentrated growth factor on facial rejuvenation
10.3760/cma.j.cn114657-20240228-00023
- VernacularTitle:水光针联合浓缩生长因子注射用于改善面部皮肤老化的疗效及安全性分析
- Author:
Yan WANG
1
;
Sujing LI
1
;
Li ZHAO
1
;
Bin DONG
1
;
Yan LI
1
;
Yonglin LI
1
;
Lei WU
1
Author Information
1. 郑州市第一人民医院整形医院毛发激光微整科，郑州 450000
- Publication Type:Journal Article
- Keywords:
Skin aging;
Concentrated growth factors;
Mesotherapy;
Facial rejuvenation
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2025;31(5):477-483
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the efficacy and safety of hydropuncture combined with concentrated growth factor (CGF) injection in improving facial aging.Methods:In this randomized controlled trial, 90 female patients with facial aging were prospectively enrolled at Plastic Surgery Hospital of Zhengzhou First People′s Hospital from January to August 2023, aged (34.0±1.5) years. Participants were randomly divided into three groups using a random number table ( n=30): hydropuncture group, CGF group, and combined hydropuncture-CGF group. All patients received monthly treatments for three sessions. Efficacy was evaluated one month after the third treatment using the VISIA skin analysis system to score pore size, skin texture, red areas, and brown spots. The clinical outcomes of facial rejuvenation and patient satisfaction were compared among the groups. Adverse reactions, including redness, pain, and allergies, were recorded. Results:Compared with the baseline data, all groups showed significant improvement in all parameters post-treatment (all P<0.01). Pretreatment scores for pores, texture, red areas, and brown spots exhibited no significant differences among groups (all P>0.05). After treatment, the combined group demonstrated the highest improvement, with significantly better scores for all parameters compared to the hydropuncture and CGF groups (all P<0.01). Patient satisfaction rates were 56.7% (17/30) in the hydropuncture group, 60.0% (18/30) in the CGF group, and 70.0% (21/30) in the combined group, with statistically significant differences ( P<0.001). No severe adverse reactions, such as infection, nodules, or hyperplasia, were observed in any group. Conclusion:Hydropuncture combined with CGF injection effectively improves facial aging with a high safety profile and no severe adverse reactions.
