Resting-state functional MRI fractional amplitude of low-frequency fluctuation for evaluating white matter function in adolescent smokers
10.13929/j.issn.1003-3289.2025.03.026
- VernacularTitle:静息态功能MRI分数低频振幅评估青少年吸烟成瘾者脑白质功能
- Author:
Daining SONG
1
;
Ting XUE
;
Dahua YU
;
Junxuan WANG
;
Wuyuan XIN
;
Jingjing DING
;
Lin LUO
;
Yongqiang KANG
Author Information
1. 内蒙古科技大学数智产业学院,内蒙古包头 014010;内蒙古模式识别与智能图像处理重点实验室,内蒙古包头 014010
- Publication Type:Journal Article
- Keywords:
adolescent;
smoking;
nicotine;
brain;
magnetic resonance imaging;
fractional amplitude of low-frequency fluctuation;
prospective studies
- From:
Chinese Journal of Medical Imaging Technology
2025;41(3):473-476
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe changes of white matter function in adolescent smoker(AS)with resting-state functional MRI(rs-fMRI)fractional amplitude of low-frequency fluctuation(fALFF)technique.Methods Forty-five adolescents(AS group)and 45 control subjects(control group)were prospectively enrolled,and brain rs-fMRI were acquired.Brain regions with fALFF being different between groups were observed,and the correlations with clinical indicators were analyzed.Results Compared with that in control group,fALFF of the right superior longitudinal fasciculus significantly elevated in AS group(FDR correct Q＜0.05),in which the peak of the cluster was positively correlated with score of Fagerstr?m test for nicotine dependence(FTND)(r=0.294,P=0.049).Conclusion White matter function changed in AS,presenting as significantly increased fALFF in right superior longitudinal fasciculus,which was positively correlated with nicotine dependence.
