Prenatal ultrasonic findings of fetal malformation of cortical development
10.13929/j.issn.1003-3289.2025.03.003
- VernacularTitle:胎儿脑皮质发育畸形产前超声表现
- Author:
Cuixia GUO
1
;
Lijuan SUN
;
Yan LIU
;
Tiejuan ZHANG
;
Li WANG
;
Jijing HAN
;
Qingqing WU
Author Information
1. 首都医科大学附属北京妇产医院北京妇幼保健院超声科,北京 100026
- Publication Type:Journal Article
- Keywords:
fetus;
malformation of cortical development;
ultrasonography
- From:
Chinese Journal of Medical Imaging Technology
2025;41(3):363-367
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe prenatal ultrasonic findings of fetal malformation of cortical development(MCD).Methods Totally 37 singleton fetuses with MCD diagnosed by fetal cranial MRI and/or genetic examination were retrospectively enrolled,and prenatal ultrasonic manifestations were observed.Results Among 37 fetuses,29(29/37,78.38％)were found with abnormal Sylvian fissure,26(26/37,70.27％)with widened/asymmetrical lateral ventricles,22(22/37,59.46％)with abnormal surface sulci,14(14/37,37.84％)with abnormal cavity of septum pellucidum(CSP)/corpus callosum(CC),11(11/37,29.73％)with midline deviation/curvature,11(11/37,29.73％)with widened subarachnoid space,10(10/37,27.03％)with head circumference＜2 standard deviation below mean value,9(9/37,24.32％)with abnormalities in the cerebellar hemisphere/vermis,7(7/37,18.92％)with abnormal echoes in the brain parenchyma,7(7/37,18.92％)with midline cysts and 2(2/37,5.41％)with enlarged ganglion eminence.Conclusion Fetal MCD mainly presented as abnormal Sylvian fissure,widened/asymmetrical lateral ventricles and abnormal surface sulci,which might accompanied by abnormal CSP/CC,midline deviation/curvature,widened subarachnoid space and abnormal head circumference in prenatal ultrasound.
