Efficacy of core resection surgery combined with triamcinolone acetonide on keloids
10.3760/cma.j.cn114657-20240624-00087
- VernacularTitle:核心切除技术联合曲安奈德治疗瘢痕疙瘩的疗效分析
- Author:
Wei WANG
1
;
Gaofeng ZHAO
1
Author Information
1. 郑州大学第一附属医院整形外科，郑州 450052
- Publication Type:Journal Article
- Keywords:
Keloid;
Core excision technique;
Triamcinolone acetonide
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2025;31(3):226-231
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical efficacy of the core excision technique combined with triamcinolone acetonide in the treatment of keloids.Methods:A total of sixty patients with keloids admitted to the First Affiliated Hospital of Zhengzhou University from September 2021 to May 2023 were prospectively included. The patients were divided into two groups using the random number table method. Observation group consisted of 30 cases, including 12 males and 18 females, with an average age of (35.7±7.9) years, and were treated with core excision combined with triamcinolone acetonide. Control group consisted of 30 cases, including 13 males and 17 females, with an average age of (36.4±7.6) years, and were treated with triamcinolone acetonide alone. The total effective rate, patient satisfaction rate, scores of the patient and observer scar assessment scale (POSAS), and the occurrence of adverse reactions were compared between the two groups after treatment.Results:The total effective rate of the observation group was 93.3% (28/30), which was higher than 73.3% (22/30) of the control group, and the difference was statistically significant ( P=0.012). The total satisfaction rate of the observation group was 90.0% (27/30), which was higher than 66.7% (20/30) of the control group, and the difference was statistically significant ( P=0.035). The POSAS scores of the patients in the observation group before and after treatment were (51.1±13.4) and (21.3±9.0) points, respectively, and those of the patients in the control group were (50.1±11.9), (29.9±11.1) points, respectively. The POSAS scores of both groups after treatment were lower than those before treatment (both P<0.001), and the POSAS score of the observation group after treatment was lower than that of the control group ( P<0.001). Regarding adverse reactions, there were two cases of delayed wound healing in the observation group and one case of tissue surface damage in the control group. Conclusion:The treatment of keloids with the core excision technique combined with triamcinolone acetonide is safe and effective.
