Comparison of efficacy of different regimens treating pruritus in patients undergoing maintenance hemodialysis

VernacularTitle:不同方案治疗维持性血液透析患者皮肤瘙痒的疗效对比
Author: Suzhen SHAO ¹ ; Yi ZHANG ¹ ; Huijuan XU ¹ ; Jian HUANG ¹ ; Fan DING ¹
Author Information

1. 九江市第六人民医院肾内科,江西九江 332000
Publication Type:Journal Article
Keywords: Sodium thiosulfate; Maintenance hemodialysis; Pruritus; Uremia
From: China Modern Doctor 2025;63(8):62-65
CountryChina
Language:Chinese
Abstract: Objective To compare clinical efficacy of different regimens in treatment of pruritus in maintenance hemodialysis(MHD)patients.Methods A total of 50 patients with MHD admitted to the Sixth People's Hospital of Jiujiang City from August 1,2022 to April 30,2024 as subjects and were divided into two groups according to random number table method.Control group(n=25)was treated with sodium thiosulfate.On this basis,gabapentin combination therapy was added in observation group(n=25).Effects of two groups were compared after 8 weeks of treatment.Results Total clinical effective rate of observation group was significantly higher than that of control group(P＜0.05).After 8 weeks of treatment,scores and total scores of all dimensions of quality of life in two groups were higher than before treatment,and observation group was higher than control group(P＜0.05).Conclusion Sodium thiosulfate combined with gabapentin in treatment of MHD patients with pruritus can not only relieve pruritus symptoms,improve sleep quality,but also have good safety.