Photodynamic chemotherapy of pathological scar: current status and prospects
10.3760/cma.j.cn114657-20250313-00060
- VernacularTitle:光动力化学疗法治疗病理性瘢痕的现状与展望
- Author:
Yang YANG
1
;
Yan SUN
1
;
Hongyi ZHAO
1
Author Information
1. 北京医院整形外科 国家老年医学中心 中国医学科学院老年医学研究院，北京 100730
- Publication Type:Journal Article
- Keywords:
Cicatrix;
Photodynamic therapy;
Photosensitizers
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2025;31(3):201-205
- CountryChina
- Language:Chinese
-
Abstract:
Pathological scar is a disease characterized by abnormal fibrous hyperplasia in the reticular layer of the dermis due to proliferation of fibroblasts, uncontrolled growth and excessive collagen deposition. Photodynamic chemotherapy, as a new treatment for pathological scar, has the advantages of being less invasive and having fewer adverse reactions. Its therapeutic principle consists of three basic elements: photosensitizers, photovoltaic illumination at a certain wavelength, and the generation of reactive oxygen species. This article primarily discusses the current application status and developmental prospects of photodynamic therapy in treating pathological scars, and also explores its limitations and challenges in scar management, aiming to provide references for laboratory research and clinical decision-making.
