Correlation between systemic inflammatory response index and prognosis of elderly patients with heart failure
10.3969/j.issn.1009-0126.2025.04.012
- VernacularTitle:全身炎症反应指数与老年心力衰竭患者预后相关性临床研究
- Author:
Jiling YU
1
;
Zhaoyuan ZHANG
;
Yifan DENG
;
Zhen FANG
;
Jun JI
;
Shenghu HE
;
Jing ZHANG
Author Information
1. 225000 扬州大学医学院
- Publication Type:Journal Article
- Keywords:
heart failure;
prognosis;
correlation of data;
risk factors;
systemic inflammatory response index
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(4):450-453
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between systemic inflammatory response index(SIRI)and the prognosis of elderly heart failure(HF)patients.Methods A retrospective study was conducted on 300 elderly HF patients with complete medical records hospitalized in our de-partment from January to December 2022.During the follow-up period for 1 year in different ways,46 of them were lost,and 254 were finally included.Baseline data,complete blood count at admission,and results of auxiliary examinations,and medicine adherence after discharge were col-lected and recorded.According to the occurrence of major adverse cardiovascular events(MACE),the subjected patients were divided into a MACE group(96 cases)and a non-MACE group(158 cases).The baseline data and relevant examination indicators were compared between the two groups,and the relevant factors for the occurrence were analyzed by using logistic regression.ROC curve analysis was employed to assess the predictive value of SIRI for MACE occurrence.Results The MACE group had significantly advanced age,larger proportion of diabetes mellitus,higher neutrophil and platelet counts,and elevated D-dimer level,but lower standardized medication rate when compared with the non-MACE group(P＜0.05,P＜0.01).The SIRI level was obviously higher in the MACE group than the non-MACE group[1.70(1.13,2.33)vs 1.29(0.85,2.06),P=0.002].Multivariate logistic regression analysis showed that atrial fibrillation,standardized medi-cation,mononuclear cells,and SIRI were independent risk factors for the occurrence of MACE in elderly HF patients(P＜0.05,P＜0.01).ROC curve analysis indicated that the AUC value of SIRI in predicting the occurrence of MACE was 0.614(95％CI:0.544-0.683),with a sensitivity of 0.813 and a specificity of 0.437.Conclusion SIRI is significantly correlated with the occurrence of MACE in elderly HF patients,and has a certain predictive value for their prognosis.
