Risk factors for heterotopic ossification in patients with proximal humerus fracture after shoulder arthroplasty
10.3760/cma.j.cn115530-20250423-00174
- VernacularTitle:人工肩关节置换治疗肱骨近端骨折术后异位骨化的危险因素分析
- Author:
Fenglong LI
1
;
Yang ZHAO
1
;
Yiming ZHU
1
;
Yi LU
1
;
Chunyan JIANG
1
Author Information
1. 首都医科大学附属北京积水潭医院运动医学科，北京市创伤骨科研究所，北京 100035
- Publication Type:Journal Article
- Keywords:
Ossification, heterotopic;
Arthroplasty, replacement;
Shoulder fractures;
Risk factor
- From:
Chinese Journal of Orthopaedic Trauma
2025;27(11):968-974
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the risk factors for heterotopic ossification (HO) after shoulder arthroplasty for patients with proximal humerus fracture.Methods:A retrospective study was conducted to analyze the clinical data of 95 patients with proximal humeral fracture who had undergone shoulder arthroplasty at Department of Sports Medicine, Beijing Jishuitan Hospital between January 2002 and December 2020. The cohort included 69 females and 26 males with an age of (66.8±11.8) years. By the Neer classification, 39 patients had three-part fractures, and 56 ones four-part fractures. According to the postoperative occurrence of HO, the patients were divided into an HO group and an HO-free group. Univariate analysis was performed for factors such as age, gender, time from injury to surgery, injury mechanism, involvement of the dominant side, surgical approach, and the Shoulder and Elbow Surgeons (ASES) score, visual analog scale (VAS) for pain, and shoulder range of motion at the final follow-up in the 2 groups. After positive indicators ( P<0.05) were screened through univariate analysis, they were included in a multivariate logistic regression model to analyze the risk factors for HO following shoulder arthroplasty. Results:All patients were followed up for (83.7±39.8) months. At the final follow-up, the incidence of HO was 34.7% (33/95). There were no statistically significant differences between the 2 groups in gender, time from injury to surgery, injury mechanism, surgical approach, or ASES score, VAS pain score, or shoulder range of motion at the final follow-up ( P>0.05). The univariate analysis showed that the age was significantly younger ( P=0.009), and the proportion of the dominant side involvement significantly lower ( P=0.016) in the HO patients. Multivariate logistic regression analysis showed that a younger age ( OR=0.947, 95% CI: 0.910 to 0.985, P=0.007) was an independent risk factor for HO in patients with proximal humerus fracture after shoulder arthroplasty. Conclusion:A younger age is the risk factor for HO after shoulder arthroplasty for patients with proximal humerus fracture.
