Adjuvant hydrogen inhalation therapy facilitates postoperative neurological function in elderly patients with cerebral hemorrhage
10.3969/j.issn.1009-0126.2025.04.021
- VernacularTitle:氢气吸入辅助治疗促进老年脑出血患者术后神经功能恢复
- Author:
Yan LI
1
;
Shengjun WANG
1
;
Yumin FENG
1
;
Wenjian ZHEN
1
;
Jinmin HAO
1
Author Information
1. 054000 邢台市中心医院神经外科二病区
- Publication Type:Journal Article
- Keywords:
cerebral hemorrhage;
therapy;
quality of life;
cognition disorders
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(4):493-496
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of adjuvant hydrogen inhalation therapy(AHIT)on postoperative neurological recovery in elderly patients with cerebral hemorrhage.Methods A pro-spective study was conducted on 100 patients with cerebral hemorrhage who underwent surgical treatment in our department between January 2021 and February 2023.They were randomly divid-ed into an observation group(AHIT)and a control group(conventional treatment),with 50 pa-tients in each group.Glasgow Coma Scale(GCS)score,NIHSS score,short from 36-item question-naire(SF-36)score,as well as levels of serum brain-derived neurotrophic factor(BDNF),insulin-like growth factor 1(IGF-1)and calcitonin gene-related peptide(CGRP),and incidence of compli-cations were compared between the two groups.Results The observation group obtained signifi-cantly higher GCS score and SF-36 scores at 4 and 8 weeks after treatment,and lower NIHSS score when compared with the control group(P＜0.01).At 8 weeks after treatment,the serum BDNF,IGF-1 and CGRP levels were notably higher in the observation group than the control group(P＜0.01).There was no statistical difference in the incidence of complications between the two groups(6.00％vs 10.00％,P＞0.05).Conclusion AHIT can significantly improve the neuro-logical recovery and quality of life of patients with cerebral hemorrhage,as well as elevate the lev-els of serum neurofunctional markers.
