Research Progress in Brain Network Mechanism of Acupuncture Intervention in Depression
10.19879/j.cnki.1005-5304.202401465
- VernacularTitle:针刺干预抑郁症脑网络机制研究进展
- Author:
Dou LIU
1
;
Huichun ZHANG
1
;
Yanan SHEN
1
;
Shujuan LI
1
;
Min XIAO
1
;
Pengfei LI
1
;
Chongbing MA
1
Author Information
1. 甘肃中医药大学针灸推拿学院,甘肃 兰州 730000
- Publication Type:Journal Article
- Keywords:
acupuncture;
depression;
brain network;
structural network;
functional network;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(4):187-192
- CountryChina
- Language:Chinese
-
Abstract:
Acupuncture is considered both safe and effective for treating depression;however,its underlying mechanism remains incompletely understood.This article reviewed the mechanisms of acupuncture in depression from the perspective of brain network dynamics.It has been found abnormal alterations in the structural and functional brain networks,including the default mode network,cognitive control network,salience network and affective network in individuals with depression.Acupuncture has been shown to enhance the diffusion anisotropy value of white matter and repair the microstructure of white matter fiber bundles in key brain regions.It can also modulate the activation the functional brain networks,either globally or in specific network segments,improve functional connectivity within and between functional networks,regulate global transmission efficiency and connectivity patterns of functional networks,restore brain network interaction balance,regulate abnormal integration of functional networks,and improve emotional regulation ability and cognitive function,in order to alleviate the clinical symptoms of depression and serve as an effective antidepressant therapy,which can provide reference for the study of acupuncture intervention in the brain network mechanism of depression.
