Correlation between intrinsic capacity and triglyceride-glucose index in older adults from a Chinese community
10.3969/j.issn.1009-0126.2025.04.011
- VernacularTitle:中国社区老年人内在能力与三酰甘油葡萄糖乘积指数的关系
- Author:
Ruihan LIU
1
;
Yutong LIU
;
Xiang ZHOU
;
Xiaomao WANG
;
Jie ZHANG
;
Fan TIAN
;
Jian CAO
Author Information
1. 解放军医学院
- Publication Type:Journal Article
- Keywords:
aged;
cross-sectional studies;
correlation of data;
logistic models
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(4):445-449
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship of TyG index and IC.Methods A cross-sectional study was conducted with 1000 older adults living in Wanshou Road Community from May to December 2023.Finally 820 participants were enrolled,and based on the TyG index,they were divided into lower TyG index group(≤7.349,404 cases)and higher TyG index group(＞7.349,416 cases).After PSM,there were only 522 participants subjected,including 261 individuals in the lower TyG index group 1 (≤7.349)and 416 ones in the higher TyG index group 2(＞7.349).Univariate and multivariate logistic regression analyses were used to assess the correlation between IC and the TyG index as both continuous and categorical variables.PSM was employed to eliminate the confounding effects of covariates to identify the relationship between TyG index and IC in different categories.Results Before PSM,the neutrophil count,WBC count,and Hcy,FPG,TC,TG and HbA1c levels were significantly lower,and lymphocyte count,monocyte count,and AST level were obviously higher in the low TyG index group than the high TyG index group(P＜0.05,P＜0.01).After PSM,the low TyG index group still had notably lower FPG,TG and HbA1c than the high TyG index group(P＜0.05,P＜0.01).ROC curve analysis revealed that the cutoff value of TyG index was 7.349.Taking 7.349 as the cutoff value and TyG index as the cate-gorical variable,multivariate logistic regression analysis displayed that TyG index was correlated with IC[OR=3.921,95％CI:2.800-5.491,P=0.001(Model 1);OR=2.744,95％CI:1.739-4.329,P=0.001(Model 2);OR=2.744,95％CI:1.805-4.171,P=0.001(Model 3);OR=2.722,95％CI:1.530-4.843,P=0.001(after PSM)],indicating that TyG index remains an independent risk factor for IC.Conclusion IC is still correlated with TyG index in community-dwelling elderly individuals under different baseline conditions after adjusting for relevant laboratory indicators.As an indicator generated from routine blood test,TyG index has advantages in terms of cost and time.With further validation,TyG may provide a direction for studying IC prediction.
