Experimental Research Progress of TCM Compounds in the Treatment of Parkinson Disease
10.19879/j.cnki.1005-5304.202402156
- VernacularTitle:中药复方治疗帕金森病实验研究进展
- Author:
Ziwei LYU
1
;
Jianqing LIANG
;
Xingling WANG
;
Guangjie SUN
Author Information
1. 甘肃中医药大学基础医学院,甘肃 兰州 730000
- Publication Type:Journal Article
- Keywords:
Parkinson disease;
TCM compounds;
experimental research;
mechanism;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(4):193-197
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson disease is a progressive neurodegenerative disease whose incidence increases year by year as the population ages.TCM compounds for the treatment of Parkinson disease has the characteristics of multiple components,targets,and pathways.Combined treatment with Western medicine can achieve synergistic effects and reduce adverse drug reactions.This article focused on the mechanism of TCM compounds for the treatment of Parkinson disease,reviewed relevant experimental studies in recent years.TCM compounds may exert therapeutic effects on Parkinson disease by regulating oxidative stress,mitochondrial dysfunction,neurotransmitters,neuroinflammation,abnormal protein aggregation,cell apoptosis,stem cell transplantation,neurotrophic factors,second messengers,and other mechanisms,in order to provide basis for clinical treatment of Parkinson disease.
