Research Progress in the Chemical Composition and Pharmacological Effects of Polygalae Japonicae Herba and Predictive Analysis on Its Quality Markers
10.19879/j.cnki.1005-5304.202403676
- VernacularTitle:瓜子金化学成分和药理作用研究进展及其质量标志物预测分析
- Author:
Mingying LIU
1
;
Chunlei WANG
;
Xiaodong LIANG
;
Yifan LIU
Author Information
1. 山东中医药大学,山东 济南 250355
- Publication Type:Journal Article
- Keywords:
Polygalae Japonicae Herba;
chemical composition;
polygalasaponin F;
pharmacological effects;
Q-marker;
predictive analysis
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(4):180-186
- CountryChina
- Language:Chinese
-
Abstract:
Polygalae Japonicae Herba has the functions of expectorant and relieving cough,promoting blood circulation and detumescence,detoxification and relieving pain.It mainly contains triterpene saponins,flavonoids,xanthones,oligosaccharides and other active components,which has many pharmacological effects,such as anti-inflammatory,analgesic,neuroprotective,anti-tumor,regulation of lipid metabolism,anti-infective preterm birth,etc.,and shows good efficacy in in the treatment of nervous,metabolic and other system diseases.This article reviewed the chemical composition and pharmacological effects of Polygalae Japonicae Herba,combining the concept of quality markers of Chinese materia medica,predicted and analyzed the quality markers of Polygalae Japonicae Herba based on plant phylogenetics,uniqueness of chemical components,efficacy of Chinese materia medica,pharmacological properties of Chinese materia medica,new pharmacological effects,detectability of chemical components,network pharmacology and molecular docking technology,in order to provide reference for the study on the material basis of the medicinal effects and quality standards of Polygalae Japonicae Herba.
