Diagnostic value of fetal cardiac ultrasound screening views in the first trimester for congenital heart disease
10.3760/cma.j.cn131148-20250508-00265
- VernacularTitle:早孕期胎儿心脏超声筛查切面显示情况对先天性心脏病的诊断价值
- Author:
Chengcheng WU
1
;
Chunya JI
;
Liqun FENG
;
Wei SHAO
;
Naimin SUN
;
Jun ZHANG
;
Zhong YANG
;
Chen LING
;
Lingling SUN
;
Qi PAN
;
Xuedong DENG
;
Linliang YIN
Author Information
1. 南京医科大学附属苏州医院 苏州市立医院超声医学中心，苏州 215002
- Publication Type:Journal Article
- Keywords:
Ultrasonography，prenatal;
First-trimester;
Congenital heart disease;
Ultrasound views;
Fetus
- From:
Chinese Journal of Ultrasonography
2025;34(9):799-804
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the diagnostic value of fetal cardiac ultrasound view visualization in the first trimester for congenital heart disease（CHD）.Methods:A retrospective analysis was performed on 13 323 singleton fetuses who underwent first-trimester（11-13 +6 weeks）ultrasound screening at the Ultrasound Medicine Center，the Affiliated Suzhou Hospital of Nanjing Medical University from January 2018 to June 2024. Cardiac views including the four-chamber view（4CV），left ventricular outflow tract view（LVOT），and Results:The study group showed significantly higher rates of "poorly visualized" 4CV，LVOT，and 3VT than the control group（2.70% vs. 0.14%， P=0.005；36.49% vs. 4.76%， P<0.001；36.49% vs.2.46%， P<0.001）. The efficacies of combination 1（any view abnormal）and combination 2（any view "poorly visualized" or "abnormal"）were comparable，with AUCs of 0.86 and 0.85（ P=0.424）. The AUCs of combination 3（3VT "poorly visualized" or any view "abnormal"）and combination 4（4CV "poorly visualized" or any view "abnormal"）were 0.88 and 0.86（ P=0.424），all significantly higher than combination 5（LVOT "poorly visualized" or any view "abnormal"，AUC=0.84，all P<0.05）. Conclusions:"Poorly visualized" cardiac views in the first trimester demonstrate good diagnostic efficacy for CHD，particularly when 3VT or 4CV are affected，warranting heightened clinical vigilance for fetal cardiac anomalies.
