Current research on common nanometallic antimicrobial coatings for orthopedic implants
10.3760/cma.j.cn115530-20240724-00314
- VernacularTitle:常见纳米金属抗菌涂层在骨科植入物中的研究现状
- Author:
Wenhao XU
1
;
Nengqi SHAO
;
Yi LUO
;
Yi CUI
Author Information
1. 大理大学临床医学院，大理 671000
- Publication Type:Journal Article
- Keywords:
Metals;
Metal nanoparticles;
Nanocomposites;
Absorbable implants
- From:
Chinese Journal of Orthopaedic Trauma
2025;27(4):363-368
- CountryChina
- Language:Chinese
-
Abstract:
Infections associated with orthopaedic implants are currently one of the major concerns of orthopaedic surgeons. Metallic antimicrobial nanocoatings have demonstrated great potential in preventing implant infections due to their excellent antimicrobial properties and biocompatibility. However, there are potential risks associated with these metal nanoparticles, such as cytotoxicity of silver and copper, and rapid dissolution of zinc and magnesium which affects implant stability. Therefore, the clinical application of nanometallic coatings still faces challenges in how to better enhance biosafety, regulate degradation rate, and enhance osseointegration. This paper reviews the progress and challenges in the application of antimicrobial nanometallic coatings on implants to provide a reference for related research.
