Value of pulmonary transit time by contrast-enhanced echocardiography in evaluating cardiac dysfunction in patients with ST-elevation myocardial infarction after PCI
10.3760/cma.j.cn131148-20250324-00157
- VernacularTitle:心脏超声造影测量肺渡越时间评估急性ST段抬高型心肌梗死患者PCI术后心功能不全的价值
- Author:
Ziqin LIU
1
;
Xin ZHONG
;
Yongjun HU
;
Huiping YOU
;
Xu XIE
;
Yutao ZHANG
;
Xiangdang LONG
Author Information
1. 湖南省人民医院（湖南师范大学附属第一医院）超声医学科，长沙 410005
- Publication Type:Journal Article
- Keywords:
Pulmonary transit time;
Contrast-enhanced ultrasound;
Cardiac insufficiency;
ST-segment elevation myocardial infarction;
Cardiac functional classification
- From:
Chinese Journal of Ultrasonography
2025;34(8):670-677
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the value of contrast-enhaoced echocardiography for measuring pulmonary transit time（PTT）in assessing heart failure after percutaneous coronary intervention（PCI）in acute ST-segment elevation myocardial infarction（STEMI）patients.Methods:From September 2023 to September 2024，120 patients with STEMI undergoing PCI at Hunan Provincial People's Hospital were prospectively selected and divided into a heart failure group（ n=42）and a non-heart failure group（ n=78）according to the guidelines. The differences in general clinical data，laboratory parameters，and echocardiographic parameters between the two groups were compared. The diagnostic efficacies of PTT，normalized PTT（nPTT），and N-terminal pro-B-type natriuretic peptide（NT-proBNP）were analyzed. Consistency between them and New York Heart Association（NYHA）heart function classification was tested. Results:Compared to the non-heart failure group，the NT-proBNP，PTT，and nPTT values in the heart failure group were significantly increased（all P<0.05）. The area under the curve（AUC）of nPTT was 0.944，better than that of PTT and NT-proBNP（AUC=0.871，0.887）. After K-means clustering reclassified patients into four levels based on nPTT values，nPTT classification showed moderate consistency with NYHA classification（Kappa=0.580， P<0.001），and nPTT differed significantly across NYHA classifications（ P<0.05）. Conclusions:PTT，as an echocardiographic index for assessing cardiac function，has similar diagnostic efficacy to NT-proBNP，the nPTT is even better. It shows moderate consistency with the NYHA classification and holds potential for differentiating overlapping NYHA grades. Importantly，it offers a fresh objective way to evaluate cardiac dysfunction after PCI in STEMI patients.
