"Two-stage theory" of thyroid thermal ablation：characteristics of each stage and proposal for a novel evaluation system
10.3760/cma.j.cn131148-20250325-00160
- VernacularTitle:甲状腺热消融“两段论”：阶段特征与评价新体系
- Author:
Jianquan ZHANG
1
;
Lei YAN
;
Jie CHENG
;
Hongqiong CHEN
;
Jialin SONG
Author Information
1. 上海百汇医院介入超声科，上海 201107
- Publication Type:Journal Article
- Keywords:
Two-stage theory;
Thermal ablation therapy;
Thyroid;
Ablation volume ratio;
Volume reduction ratio;
Ablation complex
- From:
Chinese Journal of Ultrasonography
2025;34(9):823-828
- CountryChina
- Language:Chinese
-
Abstract:
This study proposes a "two-stage" theoretical model for the thermal ablation treatment of thyroid diseases，highlighting its significant value in clinical practice. This theory categorizes thermal ablation treatment into two distinct stages：the treatment intervention stage and the clearance and absorption stage. The treatment intervention stage centers on ablation efficacy，with efficacy quantified by the ablation volume ratio（AVR），which is assessed immediately during the procedure. The clearance and absorption stage focuses on the immune-mediated clearance of necrotic tissue post-operation，with the absorption process characterized by the volume reduction rate（VRR）of the ablation area，evaluated repeatedly over an extended period. Additionally，the study introduces two key concepts：the immediate lesion volume（V 0）prior to ablation and the initial volume（V 1）of the ablation area immediately following the operation. It further develops and optimizes calculation methods for AVR and VRR. By analyzing the essential characteristics of both stages and identifying errors in traditional calculation methods，the study establishes an efficacy evaluation system and an absorption prognosis evaluation framework for thyroid thermal ablation treatment.
