Progress of neurodevelopmental imaging assessment and pathogenesis in children with congenital heart disease
10.3760/cma.j.cn131148-20241227-00687
- VernacularTitle:先天性心脏病患儿神经发育影像学评估及发病机制的研究进展
- Author:
Hairui WANG
1
;
Jiancheng HAN
1
;
Yihua HE
1
Author Information
1. 首都医科大学附属北京安贞医院 胎儿心脏病母胎医学中心，北京 100029
- Publication Type:Journal Article
- Keywords:
Congenital heart disease;
Neurodevelopmental delay or disorder;
Fetal central nervous system ultrasound;
Risk factors
- From:
Chinese Journal of Ultrasonography
2025;34(7):637-642
- CountryChina
- Language:Chinese
-
Abstract:
With advancements in prenatal diagnostic technology and postnatal clinical rescue，the survival rate of children with congenital heart disease（CHD）has significantly improved. However，neurodevelopmental delay or disorder has become the most common complication，profoundly affecting the quality of life throughout their lifetime. The risk factors and pathogenic mechanisms underlying CHD associated neurodevelopmental abnormalities remain unclear. This paper focus on the current status of neurodevelopmental outcomes in children with CHD and the potential risk factors，summarize prenatal and postnatal imaging methods for neurodevelopmental assessment，explore possible pathogenic mechanisms，and outline an integrated prenatal and postnatal neurodevelopmental evaluation framework for CHD patients. This review aims to provide comprehensive literature support for both scientific research and clinical evaluation of neurodevelopment in children with CHD.
