Clinical and multimodal ultrasonic characteristics of carotid web and carotid web with plaque
10.3760/cma.j.cn131148-20241121-00608
- VernacularTitle:颈动脉蹼与蹼伴斑块形成的临床及多模态超声特征分析
- Author:
Chao HOU
1
;
Jin HOU
;
Xixiang YI
;
Wen HE
;
Wei ZHANG
Author Information
1. 首都医科大学附属北京天坛医院超声医学科，北京 100071
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Carotid web;
Plaque;
Angle
- From:
Chinese Journal of Ultrasonography
2025;34(4):319-326
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To examine the clinical and multimodal ultrasonic characteristics differences between carotid web（CaW）and CaW with plaque，and to investigate the potential risk factors for stroke caused by CaW.Methods:A total of 215 patients who were diagnosed with CaW and simultaneously underwent contrast-enhanced ultrasound（CEUS）and superb microvascular imaging（SMI）examinations from January 2018 to October 2023 were retrospectively enrolled. Patients were divided into CaW group（ n=67）and CaW with plaque group（ n=148），the variations in clinical and multimodal ultrasonic characteristics between CaW and CaW with plaque were collected and evaluated，and univariable and multivariable Logistic regression analysis were utilized to identify possible risk factors for stroke caused by CaW. Results:Clinical features in terms of sex，age，history of smoking，alcohol，hypertension，diabetes mellitus，hyperlipidemia，and treatment，as well as ultrasonic features including web number，length，thickness，location wall，luminal stenosis，and CEUS enhancement were different between the two groups（all P<0.05）. Triangular default on SMI was present in 98.5% of CaW and 68.2% of CaW with plaque. Multivariable Logistic regression results showed that web length（ OR=1.415，95% CI=1.001-2.001， P=0.049）and angle（ OR=1.026，95% CI=1.005-1.048， P=0.016）were independent predictors of luminal stenosis in CaW；for CaW with plaque，plaque thickness（ OR=1.906，95% CI=1.343-2.704， P<0.001）and enhancement（ OR=0.186，95% CI=0.065-0.537， P=0.002）were associated with stenosis. However，no risk factors associated with stroke caused by webs were identified. Conclusions:The clinical and multimodal ultrasonic manifestations of CaW and CaW with plaque are quite different. CaW with plaque presents two modes of extension，while a triangular filling defect observed on SMI is a typical feature of CaW. No risk factors associated with stroke caused by webs are identified.
