Effect of 3D printing extravascular stent implantation on hemodynamics of large vessels in patients with nutcracker syndrome
10.3760/cma.j.cn131148-20240725-00408
- VernacularTitle:3D打印血管外支架植入对胡桃夹综合征患者大血管血流动力学的影响
- Author:
Jingxi DU
1
;
Zhen WANG
;
Ming YUAN
;
Jiahe LIANG
;
Bo ZHANG
;
Lijun YUAN
;
Yong YANG
Author Information
1. 空军军医大学唐都医院超声医学科，西安 710038
- Publication Type:Journal Article
- Keywords:
Nutcracker syndrome;
3D printing;
Extravascular stent;
Ultrasonic Doppler;
Aorta
- From:
Chinese Journal of Ultrasonography
2025;34(1):39-45
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of 3D printing extravascular stent implantation on the hemodynamics of the relevant large vessels in patients with nutcracker syndrome（NCS），and to discuss the clinical safety of this new procedure.Methods:A total of 30 NCS patients admitted to Tangdu Hospital Affiliated to Air Force Military Medical University from May to December 2023 were prospectively included. All the patients were received laparoscopic 3D printing extravascular stent implantation for NCS treatment. Whether the lumbago，abdominal pain，hematuria，proteinuria and varicocele had improved after the stent implantation were observed. The inner diameter，blood flow velocity of left renal vein，abdominal aorta，superior mesenteric artery and the diameter of inferior vena cava were measured by ultrasound 1 day before surgery and 8 days after surgery，respectively.In addition，the carotid-femoral pulse wave velocity（cfPWV）was measured by a newly developed method，by which the arterial stiffness could be detected based on Doppler ultrasound. The blood flow Doppler spectra of each subject were recorded at the right common carotid artery and the right common femoral artery，respectively，then based on that，the cfPWV was automatically calculated by this new technique. The above internal diameters，blood flow velocity and cfPWV were compared before and after the laparoscopic 3D printing extravascular stent implantation.Results:Among the 30 patients，the postoperative blood flow velocity at the left renal vein compression site was significantly lower than that before surgery［（50.7 ± 14.8）cm/s vs（122.1 ± 24.1）cm/s， P<0.001）］，and the clinical symptoms，including lumbago and abdominal pain，hematuria，proteinuria and varicocele were significantly improved（all P<0.05）. There were no significant changes in the internal diameter，blood flow velocity of abdominal aorta，superior mesenteric artery and the diameter of inferior vena cava，and cfPWV before and after operation（all P>0.05）. Conclusions:The 3D printing extravascular stent implantation through laparoscope can effectively improve left renal vein compression in patients with NCS，and cause no significant change in large arterial hemodynamics，suggesting that this surgical method is a safe and reliable treatment for patients with NCS.
