Status and influencing factors of feeding intolerance in patients with enteral nutrition after lung transplantation
10.3761/j.issn.0254-1769.2025.07.013
- VernacularTitle:肺移植术后肠内营养患者喂养不耐受的现状及影响因素分析
- Author:
Lihua CHEN
1
;
Yao HUANG
1
;
Qingqing SHENG
1
;
Yufeng TAN
1
;
Shuqin ZHANG
1
;
Xiaoqun HUANG
1
;
Mengmeng XU
1
Author Information
1. 510000 广州市 广州医科大学附属第一医院广州呼吸健康研究院重症医学科
- Publication Type:Journal Article
- Keywords:
Lung Transplantation;
Enteral Nutrition;
Feeding Intolerance;
Root Cause Analysis;
Nursing Care
- From:
Chinese Journal of Nursing
2025;60(7):849-855
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the status of feeding intolerance in patients with enteral nutrition after lung transplantation and analyze its influencing factors,to provide a reference for formulating a reasonable enteral nutrition plan and improving patients'nutritional status.Methods Convenient sampling method was used to retrospectively collect the clinical data of 115 patients who received enteral nutrition support after lung transplantation and were hospitalized in the ICU of a tertiary hospital in Guangdong Province from August 2022 to November 2023.According to the occurrence of feeding intolerance during ICU hospitalization,the patients were divided into a feeding tolerance group and a feeding intolerance group.Univariate and logistic regression analysis were used to analyze the influencing factors of feeding intolerance patients with enteral nutrition after lung transplantation.Results Within 7 days of initiating enteral nutrition,a total of 63 patients developed feeding intolerance,with an incidence of 54.78%.Among them,the incidence of feeding intolerance was relatively high within 1 to 3 days after initiating enteral feeding.The clinical manifestations of feeding intolerance were diarrhea,bloating,gastric retention,vomiting/regurgitation,among which the diarrhea was the highest incidence(87.30%).Logi-stic regression analysis showed that intraoperative net balance volume(OR=0.999),intraoperative blood transfusion(OR=1.001)volume and diabetes history(OR=0.170)were independent influencing factors for feeding intolerance in patients with enteral nutrition after lung transplantation(P<0.05).Conclusion There was a high incidence of feed-ing intolerance in patients with enteral nutrition after lung transplantation.Patients undergoing lung transplantation who have a high net intraoperative fluid balance,receive a low volume of intraoperative blood transfusions,and have a history of diabetes are at a lower risk of developing feeding intolerance when receiving postoperative enteral nutrition.When starting enteral nutrition,medical staff should dynamically evaluate the risk factors of feeding intolerance,screen high-risk patients as early as possible,and formulate reasonable enteral nutrition programs to improve the nutritional status of patients and promote their rehabilitation.