Research progress of multimodal imaging in idiopathic generalized epilepsy with cognitive impairment
- VernacularTitle:特发性全面性癫痫伴认知障碍的多模态影像学研究进展
- Author:
Fei LI
1
;
Ting LIU
1
;
Binji LIANG
1
;
Huixia LIN
1
;
Xuemeng CUI
1
;
Tingting JI
1
;
Qifu LI
1
Author Information
- Publication Type:Journal Article
- Keywords: Epilepsy; Idiopathic generalized epilepsy; Cognitive impairment; Magnetic resonance imaging
- From: Chinese Journal of Neurology 2025;58(12):1324-1330
- CountryChina
- Language:Chinese
- Abstract: With the rapid development of neuroelectrophysiology, neuroimaging and other technologies, a large amount of evidence has shown that the occurrence and development of idiopathic generalized epilepsy (IGE) are closely related to the cortical-subcortical neural network. This article intends to review the relevant research on how the cerebral cortex and subcortical structures such as the thalamus, basal ganglia, and cerebellum are involved in the cognitive impairment of IGE, as well as the important subcortical neural nuclei targets currently targeted in the treatment of drug-resistant epilepsy by neuromodulation, to evaluate the feasibility of neuromodulation therapy in clinical practice.
