Impact of bundle intervention measures on incidence of catheter-related infections in ICU patients of neurosurgery department
10.11816/cn.ni.2025-248382
- VernacularTitle:集束化干预措施对神经外科ICU导管相关感染发病率的影响
- Author:
Ya YANG
1
;
Mei HAUNG
1
;
Jiayan DING
1
;
Xiaofang FU
1
;
Yu ZHENG
1
;
Haiqun BAN
1
Author Information
1. 上海交通大学医学院附属仁济医院感染管理办公室,上海 200127
- Publication Type:Journal Article
- Keywords:
Neurosurgery intensive care unit;
Hospital-associated infection;
Catheter-related infection;
Bundle;
In-tervention measure;
Interrupted time series
- From:
Chinese Journal of Nosocomiology
2025;35(6):945-949
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the impact of bundle intervention measures on incidence of catheter-related in-fections in patients of neurosurgery intensive care unit(NICU).METHODS The related data regarding to incidence rates of hospital-associated infections and utilization rates of catheters were collected from the NICU patients of Renji Hospital,Shanghai Jiaotong University from 2007 to 2022.The effect of the bundle intervention measures on reducing the incidence of catheter-related infections was analyzed by means of interrupted tune series(ITS)method.RESULTS There was significant difference in the decline trend of incidence of the infections during the study(the trend x2=91.978,P＜0.001).ITS analysis showed that the utilization rate of catheters only presented the decline trend after the intervention(β2=-0.667,P=0.042),the utilization rate of ventilator tubes only de-clined after the intervention(β3=-26.375,P＜0.001).Th utilization rate of central venous catheters showed a downward trend before the intervention(β1=-2.525,P＜0.001)but did not change significantly after the inter-vention.The incidence of central line-associated bloodstream infection(CLABSI)was decreased(RR=0.268,95％CI:0.124 to 0.581),however,there was significant difference in the change of slope(RR=0.912,95％CI:0.730 to 1.140).The incidence of catheter-associated urinary tract infection(CAUTI)showed a downward trend(RR=0.796,95％CI:0.647 to 0.975),however,there was no significant difference in the change of the level(RR=1.543,95％CI:0.816 to 3.005).The incidence of ventilator-associated pneumonia(VAP)showed a downward trend(RR=0.829,95％CI:0.767 to 0.895),however,there was no significant difference in the change of the level(RR=0.817,95％CI:0.595 to 1.114).CONCLUSIONS The bundle intervention measures may effectively reduce the incidence of catheter-related infections.The incidence rates of the catheter-related infections vary in the chan-ging trends after the interventions are taken,indicating that it is necessary to comprehensively take the character-istics of catheter-related infections into account when carrying out the bundle intervention measures and continu-ously optimize the control strategies.
