Correlation between mild-stenotic parent artery plaques and lesion imaging features in lenticulostriate recent small subcortical infarction: an intracranial vascular high-resolution magnetic resonance imaging study
10.3760/cma.j.cn113694-20241230-00830
- VernacularTitle:豆纹动脉区近期皮质下小梗死影像特征与轻度狭窄载体动脉责任斑块的相关性：一项颅内血管高分辨磁共振研究
- Author:
Dandan ZHANG
1
;
Ce ZONG
1
;
Yongli TAO
1
;
Zhengrong WU
1
;
Sai WANG
1
;
Yuming XU
1
;
Yuan GAO
1
Author Information
1. 郑州大学第一附属医院神经内科，郑州 450052
- Publication Type:Journal Article
- Keywords:
Brain infarction;
Magnetic resonance imaging;
Middle cerebral artery;
Atherosclerosis;
Lowest slice involved;
Total number of slices involved
- From:
Chinese Journal of Neurology
2025;58(6):591-598
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the correlation between the lesion imaging characteristics and the parent artery plaques detected by high-resolution magnetic resonance imaging (HR-MRI) in patients with recent small subcortical infarction (RSSI) in the lenticulostriate artery territory with mild stenosis of the parent artery.Methods:Consecutive patients with RSSI in the lenticulostriate artery territory admitted to Department of Neurology, the First Affiliated Hospital of Zhengzhou University from January 2020 to December 2022 were prospectively enrolled. Patients with stenosis of <50% in the ipsilateral middle cerebral artery (MCA) who had completed HR-MRI were included. The RSSI lesion characteristics, such as the lowest slice involved (LS), total number of slices involved (TNS) were evaluated based on serialized axial levels of diffusion weighted imaging. HR-MRI was utilized to assess the presence of dorsal superior plaques in the M1 segment of the responsible MCA. Patients were divided into plaque group and non-plaque group based on the presence or absence of plaque. Logistic regression analysis was carried out to identify the lesion characteristics associated with the presence of dorsal superior plaques in the MCA. A receiver operating characteristic (ROC) curve was employed to estimate the predictive efficacy of these parameters for MCA plaques using the area under the curve (AUC) and the optimal cut-off point.Results:A total of 112 patients were incorporated into the final analysis. The age of these patients was (57.08±11.90) years, and 78 patients (69.64%) were male. Plaques were detected on the dorsal superior wall of the MCA in 57 cases (50.89%) as the plaque group, and the other 55 cases (49.11%) were regarded as the non-plaque group. Multivariate Logistic regression revealed that LS was significantly associated with MCA plaques ( OR=0.674, 95% CI 0.485-0.937, P=0.019). The optimal cut-off point (LS≤1) was determined by ROC curve analysis (AUC=0.640, P=0.007). Conclusion:The findings suggest that in RSSI patients with mild stenosis of the parent artery, an LS≤1 is notably associated with the presence of dorsal superior plaques on MCA as detected by HR-MRI.
