Impact of male body mass index on pregnancy complications in their partners and offspring birth outcomes

VernacularTitle:男性体重指数对其伴侣妊娠期并发症及子代出生结局的影响
Author: Xiaoqian XU ¹ ; Ye ZHENG ; Longfeng XU ; Rong TANG
Author Information

1. 山东大学医学融合与实践中心，济南　250012
Publication Type:Journal Article
Keywords: Body mass index; Fathers; Pregnancy complications; Epigenomics
From: Chinese Journal of Perinatal Medicine 2024;27(12):1083-1087
CountryChina
Language:Chinese
Abstract: The influence of female pre-pregnancy body mass index (BMI) on maternal and neonatal outcomes is well recognized. Similarly, the role of male BMI on pregnancy complications in their partners and offspring birth outcomes has also caught increasing public attention. Male obesity may negatively affect their partners and fetuses through a variety of mechanisms, such as changes in semen composition, sperm morphology and physiology, and epigenetic modifications. Unhealthy lifestyles shared by couples can also contribute to these issues. Some animal studies have attempted to explore the related mechanisms. This article reviews the effect of male BMI on female pregnancy complications and neonatal outcomes, and investigations into the potential mechanisms involved using animal models. This study emphasizes the importance of taking paternal factors into diagnostic evaluations for healthcare professionals and the significance of male BMI control for better protecting their partners and offspring.