Research progress on the mechanism and intervention of behavioral and psychological symptoms in Alzheimer′s disease
10.3760/cma.j.cn113694-20240927-00641
- VernacularTitle:阿尔茨海默病精神行为症状的机制及其干预研究进展
- Author:
Xuerui PANG
1
;
Miao FANG
;
Xingqi WU
;
Guixian XIAO
;
Yulong DAI
;
Shanshan ZHOU
;
Panpan HU
;
Kai WANG
Author Information
1. 安徽医科大学第一附属医院神经内科 认知与神经精神疾病安徽省重点实验室 安徽省神经精神疾病与心理健康协同创新中心,合肥230022
- Publication Type:Journal Article
- Keywords:
Alzheimer disease;
Anxiety;
Depression;
Sleep disorders;
Delusions;
Hallucinations;
Behavior and behavior mechanisms
- From:
Chinese Journal of Neurology
2025;58(5):546-552
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer′s disease is a serious neurodegenerative disorder. Approximately 80% to 90% of patients are accompanied by behavioral and psychological symptoms of dementia (BPSD), which manifest as a series of behavioral, psychological and mental abnormalities. These abnormalities can accelerate the cognitive deterioration and premature death of patients, and thus are regarded as important clinical symptoms. However, the pathogenesis of BPSD is still unknown, and treatment methods are limited. The pathogenesis of BPSD from the perspective of neuroimaging and pathophysiology, and possible treatment measures were analyzed in this article, in order to provide references for the early diagnosis and treatment of BPSD.