Research progress on bladder and urethral dysfunction in Parkinson′s disease
10.3760/cma.j.cn113694-20240821-00572
- VernacularTitle:帕金森病膀胱尿道功能障碍的研究进展
- Author:
Hong JIN
1
;
Tianyu MA
1
;
Jing CHEN
1
;
Chunfeng LIU
1
Author Information
1. 苏州大学附属第二医院神经内科,苏州215004
- Publication Type:Journal Article
- Keywords:
Parkinson disease;
Neurodegenerative disease;
Bladder and urethral dysfunction;
Lower urinary tract symptoms
- From:
Chinese Journal of Neurology
2025;58(5):540-545
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson′s disease (PD) is a neurodegenerative disorder prevalent among the elderly, characterized by the degeneration of dopaminergic neurons in the substantia nigra. The motor symptoms of PD include resting tremor, bradykinesia, rigidity, and postural gait disturbances. Additionally, non-motor symptoms such as depression, pain, cognitive impairment, sleep disorders, and autonomic dysfunction are gaining increasing attention. Among these, bladder and urethral dysfunction is one of the most common manifestations of autonomic dysfunction and significantly impacts patients′ quality of life in the later stages of the disease. This article provides a review of recent research on the epidemiology, pathogenesis, and treatment of bladder and urethral dysfunction in PD, aiming to enhance the understanding and management of urinary symptoms associated with PD.