Focus on the diagnosis and treatment of parainfectious encephalopathy
10.3760/cma.j.cn113694-20241221-00811
- VernacularTitle:重视副感染脑病的诊治
- Author:
Hongzhi GUAN
1
Author Information
1. 中国医学科学院北京协和医院神经科，北京 100730
- Publication Type:Journal Article
- Keywords:
Infection;
Parainfectious encephalopathy;
Respiratory virus;
Cytokines;
Immunotherapy
- From:
Chinese Journal of Neurology
2025;58(5):457-461
- CountryChina
- Language:Chinese
-
Abstract:
Parainfectious encephalopathy is a group of acute encephalopathy syndromes secondary to systemic infectious diseases, especially respiratory virus infection. Parainfectious encephalopathy is not caused by direct invasion of the central nervous system by viruses, nor is it a specific autoimmune encephalitis mediated by adaptive immunity. It may be related to inflammatory syndromes caused by cytokine storms and individual genetic factors. Parainfectious encephalopathy has diverse clinical features, and it can be classified into 11 phenotypes. The mortality and disability rates of severe phenotypes are high. Timely diagnosis and immunotherapy can help improve prognosis.
