Application of quantitative electroencephalogram in the early diagnosis of Alzheimer′s disease
10.3760/cma.j.cn113694-20240821-00570
- VernacularTitle:定量脑电图在阿尔茨海默病早期诊断中的应用
- Author:
Yixing WANG
1
;
Yan WANG
1
;
Lin SONG
1
;
Yifeng DU
1
Author Information
1. 山东第一医科大学附属省立医院神经内科，济南 250021
- Publication Type:Journal Article
- Keywords:
Alzheimer disease;
Early diagnosis;
Quantitative electroencephalogram;
Neurophysiology
- From:
Chinese Journal of Neurology
2025;58(4):440-444
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer′s disease (AD) is the most common reason of dementia in the elderly, which brings a heavy burden to families and society. Due to its high prevalence, hidden onset, and poor effect of late treatment, it is urgent to improve the level of early diagnosis of AD, and slow or reverse the progression of the disease through early detection and intervention. Quantitative electroencephalogram (qEEG) can directly reflect the real-time discharge of brain neurons, and has a unique advantage in the early diagnosis of AD due to its characteristics of non-invasive, cheap, convenient and high time resolution. The ideas and methods of early diagnosis and differential diagnosis of AD by multi-angle qEEG spectrum analysis, synchronization and complexity analysis are steadily developing. It is expected to be one of the neurophysiological biomarkers for early screening and diagnosis of AD. The present paper reviews the typical qEEG characteristics of AD and its early stages, summarizes and compares the application and potential of commonly used qEEG techniques in the early diagnosis of AD.
