Role of genetic factors in large atherosclerotic stroke in young adults
10.3760/cma.j.cn113694-20240812-00544
- VernacularTitle:遗传因素在大动脉粥样硬化青年卒中中的作用研究进展
- Author:
Juan HUANG
1
;
Xiaobo LI
1
;
Yiwei CHEN
1
;
Zhiyi JIANG
1
;
Panyao LONG
1
;
Yi YUAN
1
;
Shuntong HU
1
Author Information
1. 中南大学湘雅三医院神经内科，长沙 410013
- Publication Type:Journal Article
- Keywords:
Stroke;
Adult;
Atherosclerosis;
Genetics;
Polymorphism, single nucleotide
- From:
Chinese Journal of Neurology
2025;58(2):210-219
- CountryChina
- Language:Chinese
-
Abstract:
Genetic factors are often involved in the pathogenesis of young adult stroke, and its subtype, atherosclerotic type of large arteries, may be caused by a combination of genetic and environmental factors, but little is known about its underlying pathogenesis. To provide clues for better understanding of identifying relevant stroke etiological genetic factors and adopting effective preventive strategies, the role of genetic factors in atherosclerosis and related risk factors was described, and the possible genetic mechanisms of large-artery atherosclerotic stroke in young people were explored, which may be further investigated in future research in the following areas: etiological typing of stroke in young people and the related genetic mechanisms; modifiable vascular risk factors and the development of secondary prevention strategies; high-resolution vascular imaging magnetic resonance imaging in the etiological typing of stroke in young people and the pathogenesis of premature atherosclerosis and vulnerable plaques.
