Ultrasonographic study of postsystolic shortening of the left ventricle in hypertrophic obstructive cardiomyopathy
10.3969/j.issn.1673-9701.2025.30.007
- VernacularTitle:肥厚型梗阻性心肌病左心室收缩后缩短的横断面超声研究
- Author:
Juan WAN
1
;
Zhaoyou LIU
1
Author Information
1. 江西中医药大学附属医院超声科,江西南昌 330006
- Publication Type:Journal Article
- Keywords:
Real time three-dimensional echocardiography;
Hypertrophic obstructive cardiomyopathy;
Post-systolic shortening
- From:
China Modern Doctor
2025;63(30):30-33
- CountryChina
- Language:Chinese
-
Abstract:
Objective This study aimed to assess the changes in post-systolic shortening(PSS)of the left ventricular myocardium in patients with hypertrophic obstructive cardiomyopathy(HOCM)using real time three-dimensional echocardiography(RT-3DE)technology.Methods A total of 39 HOCM patients from the Department of Ultrasound,Affiliated Hospital of Jiangxi University of Chinese Medicine were included as HOCM group,and 41 healthy individuals of similar age and gender who underwent physical examinations during the same period were selected as control group.RT-3DE examinations were performed on all participants to compare conventional echocardiographic parameters,left ventricular diastolic function parameters,the distribution of PSS in different segments of the left ventricular wall,and the average post-systolic index(PSI)of the left ventricular wall.Results HOCM group exhibited significant elevations in left atrial diameter,diastolic left ventricular posterior wall thickness,left ventricular ejection fraction,left ventricular outflow tract peak pressure gradient,mitral regurgitation,and interventricular septum thickness compared to control group(P＜0.05).In contrast,left ventricular end-diastolic diameter and left ventricular end-systolic diameter were significantly decreased in HOCM group(P＜0.05).There were no significant differences in the ratio of peak early diastolic mitral inflow velocity to peak late diastolic mitral inflow velocity and the ratio of peak early diastolic mitral inflow velocity to the peak early diastolic tissue velocity of the lateral mitral annulus between two groups.However,deceleration time of mitral early diastolic inflow velocity was higher and peak late diastolic tissue velocity at mitral lateral annulus was lower in HOCM group compared to control group(P＜0.05).The probability of PSS occurring in the basal,mid,and apical segments of the interventricular septum was significantly higher in HOCM group compared to control group(P＜0.05).The average PSI in HOCM group was significantly increased compared to control group(P＜0.05).Conclusion Patients with HOCM may exhibit early myocardial shortening in the left ventricle.The application of RT-3DE technology for quantitative analysis can detect the occurrence of PSS in different segments of the left ventricle,which may have implications for clinical evaluation and intervention.
