Analysis of risk factors of bronchopneumonia and lobar pneumonia caused by Mycoplasma pneumoniae
10.3969/j.issn.1673-9701.2025.29.010
- VernacularTitle:儿童肺炎支原体支气管肺炎与大叶性肺炎的相关危险因素分析
- Author:
Xiaolin SHI
1
;
Dongjing TANG
1
;
Meihui WU
1
Author Information
1. 青岛大学附属威海市立第二医院(威海市妇幼保健院),山东威海 264200
- Publication Type:Journal Article
- Keywords:
Mycoplasma pneumoniae;
Bronchopneumonia;
Lobar pneumonia;
Risk factor
- From:
China Modern Doctor
2025;63(29):39-42
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the laboratory indicators of bronchopneumoniaand lobar pneumonia caused by Mycoplasma pneumoniae(MP)in children,and to explore the risk factors of lobar pneumonia in children.Methods A total of 424 children diagnosed with pneumonia caused by MP infection,admitted to the Second Hospital of Weihai,Qingdao University(Weihai Maternal and Child Health Hospital)from July to October 2023 were selected as subjects.Based on chest X-ray findings at admission,the childron were divided into bronchopneumonia group(n=178)and lobar pneumonia group(n=246).Age,hospitalization duration,laboratory parameters,and clinical characteristics were compared between two groups.Results The age and hospitalization duration of children with lobar pneumonia group were significantly higher than those in bronchopneumonia group(P＜0.05).The lactic acid dehydrogenase(LDH),adenosine deaminase(ADA),C-reactive protein(CRP),erythrocyte sedimentation rate(ESR),and D-dimer levels in lobar pneumonia group were markedly elevated compared to bronchopneumonia group(P＜0.05).Rates of mixed infections,pleural effusion,concurrent organ damage,infection with multidrug-resistant MP,and bronchoscopy procedures were higher in lobar pneumonia group than those in bronchopneumonia group(P＜0.05).Elevated LDH,ADA,CRP,ESR,D-dimer levels and older children were identified as risk factors for developing lobar pneumonia following MP infection.LDH,ADA,CRP,ESR,D-dimer demonstrated predictive value for lobar pneumonia development,with their area under the curve(AUC)values were 0.612,0.704,0.659,0.645,and 0.679 respectively.When combined for prediction,the AUC was 0.793.Conclusion There are significant differences in various laboratory indicators between bronchopneumonia and lobar pneumonia caused by MP,and comprehensive analysis of multiple indicators is helpful for differential diagnosis of two types of pneumonia.
