The changes of core symptoms and nursing implications for lymphoma patients with chemotherapy
10.3761/j.issn.0254-1769.2025.20.009
- VernacularTitle:淋巴瘤患者化疗期核心症状的纵向研究及护理对策
- Author:
Jin HE
1
;
Lina FENG
1
;
Jinli TIAN
1
;
Xiaomeng ZHU
1
;
Xiaotong XU
1
Author Information
1. 300060 天津市 天津医科大学肿瘤医院/国家恶性肿瘤临床医学研究中心/天津市肿瘤防治重点实验室/天津市恶性肿瘤临床医学研究中心淋巴瘤内科
- Publication Type:Journal Article
- Keywords:
Lymphoma;
Symptom Network Analysis;
Core Symptoms;
Longitudinal Studies;
Nursing Care
- From:
Chinese Journal of Nursing
2025;60(20):2492-2498
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of core symptoms and nursing strategies for lymphoma patients during chemotherapy using a dynamic network analysis model,and provide a reference for precise symptom intervention.Methods A longitudinal study was conducted,and lymphoma patients undergoing chemotherapy in the Department of Lymphoma at a tertiary hospital in Tianjin from September 2021 to December 2023 were conveniently sampled.The Lymphoma Patient Symptom Assessment Scale was used to track symptoms at 3 time points:7 to 14 days after the 1st treatment cycle(T1),the 3rd cycle(T2),and the 6th cycle(T3).Dynamic symptom network analysis,including network relationships,core symptoms,and bridge symptoms,was performed using R software.Results During the research process,135 participants withdrew,resulting in a final inclusion of 865 cases for analysis.Fatigue exhibited the highest incidence rate(34.80％)at T1;alopecia was the most prevalent symptom(58.03％and 53.64％,respectively)at T2 and T3.The T1→T2 dynamic network analysis showed that fever had the highest out-expected influence(EI=0.551)and bridge expected influence(EI=0.225).The T2→T3 dynamic network analysis showed that limb numbness exhibited the highest out-expected influence(EI=0.203)and bridge-expected influence(EI=0.170).Reliability tests indicated that both dynamic networks demonstrated moderate accuracy but suboptimal stability.Conclusion Fatigue was the most common symptom at T1;alopecia was the most prevalent symptom at T2 and T3.Fever was the core symptom and bridging symptom in the T1→T2 symptom network,whereas limb numbness assumed the role of the core symptom and bridging symptom in the T2→T3 symptom network.The clinical practitioners could take high-incidence symptoms and core symptoms as intervention targets to develop precise symptom management strategies for lymphoma patients undergoing chemotherapy.
