Research Progress of Tongqiao Huoxue Decoction and Its Modified Prescriptions in Treating Neurological Diseases
10.19879/j.cnki.1005-5304.202503334
- VernacularTitle:通窍活血汤及加减方治疗神经系统疾病研究进展
- Author:
Wentao HAO
1
;
Ling LI
;
Shangzhi WU
;
Wanxia JING
;
Yang WANG
Author Information
1. 陕西中医药大学,陕西 咸阳 712046
- Publication Type:Journal Article
- Keywords:
Tongqiao Huoxue Decoction;
neurological diseases;
mechanism;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(11):193-196,后插1
- CountryChina
- Language:Chinese
-
Abstract:
The incidence,disability and mortality of nervous system diseases have risen sharply worldwide.At present,the pathogenesis and mechanism of nervous system diseases have not been clarified.Tongqiao Huoxue Decoction in Yi Lin Gai Cuo has the effects of promoting blood circulation and removing blood stasis,dredging orifices and activating collaterals.This article reviewed the clinical trials and basic research of Tongluo Huoxue Decoction and its modified prescriptions in the treatment of neurological diseases in recent years.It showed that this prescription is often used in the treatment of blood stasis syndrome at the brain orifices,which has a significant effect on improving brain function and treating a variety of intractable diseases related to brain nerves;its pharmacological mechanisms involve regulating neurotransmitters,restoring nerve function,inhibiting oxidative stress along with inflammatory responses,optimizing hemodynamics and blood rheology retarding vascular remodeling,and promoting angiogenesis.