Clinical application of laboratory examination for autoimmune hemolytic anemia
10.3760/cma.j.cn114452-20250526-00306
- VernacularTitle:自身免疫性溶血性贫血实验室检查的临床应用
- Author:
Shuang LIANG
1
;
Jun WU
1
Author Information
1. 首都医科大学附属北京积水潭医院医学检验中心，北京100035
- Publication Type:Journal Article
- Keywords:
Autoimmune hemolytic anemia;
Clinical laboratory techniques;
Diagnostic techniques
- From:
Chinese Journal of Laboratory Medicine
2025;48(11):1375-1381
- CountryChina
- Language:Chinese
-
Abstract:
The Laboratory examination plays a pivotal role in the diagnosis and classification of autoimmune hemolytic anemia (AIHA). The direct antiglobulin test (DAT) is the cornerstone of AIHA diagnosis. Technological advancements in the laboratory significantly improve the detection sensitivity of autologous erythrocyte antibodies. However, there remains a deficiency in appropriate laboratory indicators for the diagnosis of DAT-negative AIHA, early screening, prediction, and prognostic assessment of AIHA. This review summarized the present laboratory tests and laboratory diagnosis procedure of AIHA and addressed the challenges and development perspectives, so as to improve clinical diagnosis and treatment, and to elevate the high-quality development of laboratory medicine in the field of AIHA.
