Research progress of microfluidic chip technology in rapid detection of drug-resistant bacteria
10.3760/cma.j.cn114452-20250210-00071
- VernacularTitle:微流控芯片技术在耐药菌快速检测中的研究进展
- Author:
Min LI
1
;
Xiaochen YU
1
;
Xiuru GUAN
1
Author Information
1. 哈尔滨医科大学附属第一医院检验科，哈尔滨 150000
- Publication Type:Journal Article
- Keywords:
Bacteria;
Drug resistance;
Microfluidic analytical techniques
- From:
Chinese Journal of Laboratory Medicine
2025;48(9):1242-1247
- CountryChina
- Language:Chinese
-
Abstract:
Drug resistance refers to the reduced or lost sensitivity of microorganisms to key drugs used in clinical (routine) treatment. Antimicrobial resistance poses a significant threat to global public health and safety. The misuse and abuse of antibacterial drugs not only causes inefficient treatment of bacterial infectious diseases, but also exacerbates the evolution of bacterial antimicrobial resistance and the spread of antimicrobial-resistant bacteria. As one of the cutting-edge scientific techniques, microfluidic chip technology has shown extensive application potentials in various fields. In the rapid detection of drug-resistant bacteria, microfluidic chip technology has the advantages of fast speed, high degree of automation, and the ability to perform multiple detections. This article focuses on bacterial antimicrobial resistance, and briefly introduces the principle of microfluidic chips, systematically outlines the application of microfluidic technology in antimicrobial resistance detection, and provides a theoretical reference for the diagnosis of clinical bacterial infectious diseases.
