A case of encapsulated empyema caused by Parvimonas micra infection

VernacularTitle:微小小单胞菌感染致包裹性脓胸1例
Author: Guihua RAO ¹ ; Qiang WANG ; Fang ZHAO ; Mingliang CHEN
Author Information

1. 复旦大学附属闵行医院检验科，上海　201199
Publication Type:Journal Article
Keywords: Empyema, pleural; Pleural effusion; Parvimonas micra
From: Chinese Journal of Laboratory Medicine 2025;48(9):1231-1234
CountryChina
Language:Chinese
Abstract: A 37-year-old male patient was admitted to a certain tertiary hospital in Shanghai on May 10, 2024 due to "sudden cough accompanied by chest pain for 2 days". Smear examination of pleural effusion revealed Gram-positive cocci. A positive result was reported after 3.8 days of anaerobic culture, and the isolate was identified as Parvimonas micra by mass spectrometry. Based on the patient′s medical history, imaging and etiological examination results of pleural effusion, the patient was diagnosed with encapsulated empyema caused by Parvimonas micra infection. After anti-infection treatment with imipenem and linezolid and pleural effusion drainage, the patient improved and was discharged. Whole-genome sequencing analysis revealed that this bacterium carried the drug resistance gene tetM and phylogenetic tree analysis showed that it was closely related to a strain from an apical abscess in South Korea.