Application and Progress of Organs-on-chips Technology in Chinese Materia Medica Research
- VernacularTitle:器官芯片技术在中药研究中的应用与进展
- Author:
Wei CHEN
1
;
Weidong ZHANG
1
;
Quan ZHAO
1
;
Fang WANG
1
;
Wei HUANG
1
;
Chanming LIU
1
;
Yueqin ZHU
1
;
Jing ZHANG
1
;
Feng HUA
1
Author Information
- Publication Type:Journal Article
- Keywords: organs-on-chips; Chinese materia medica; safety evaluation; disease model; review
- From: Chinese Journal of Information on Traditional Chinese Medicine 2025;32(11):187-192
- CountryChina
- Language:Chinese
- Abstract: In recent years,organs-on-chips(OOCs)technology has gradually matured and been recognized by regulatory agencies,playing a key role in the construction of pathophysiological models,pharmacodynamic screening,toxicological evaluation and other fields,providing guidance for the research and development of innovative drugs of Chinese materia medica and the clinical application of classic prescriptions.This article reviewed the application progress of OOCs technology in the research of Chinese materia medica from four dimensions:pharmacodynamic and toxicological evaluation,quality control,active component analysis and innovative drug research and development,in order to provide a reference for the precise application of this technology in the field of Chinese materia medica.
