Research progress in platelet blood group detection technology
10.3760/cma.j.cn114452-20250415-00234
- VernacularTitle:血小板血型检测技术研究进展
- Author:
Jinyu SHEN
1
;
Gangqing PAN
;
Shujuan CHEN
;
Xuerong SUN
;
Jie RUAN
Author Information
1. 广东医科大学医学技术学院，东莞523808
- Publication Type:Journal Article
- Keywords:
Platelets;
Blood type;
Antibody;
Human leukocyte antigen;
Human platelet antigen
- From:
Chinese Journal of Laboratory Medicine
2025;48(8):1101-1106
- CountryChina
- Language:Chinese
-
Abstract:
With the advancement of transfusion medicine and the widespread use of platelet-related preparations, platelet transfusion has become a critical therapeutic intervention in clinics. To enhance the safety and efficacy of platelet transfusion, platelet blood group typing has been increasingly implemented in clinical practice, accompanied by the emergence of novel testing technologies and methodologies, such as flow cytometric immuno-bead array analysis, microtiter plate-based immobilized recombinant single antigen enzyme-linked immunosorbent assay and third-generation sequencing. Significant progress has been made in platelet blood group detection, including improvements in serological testing methods, integration and optimization of multi-platform detection technologies, and the development of high-throughput molecular genotyping techniques. The advancement in platelet blood group detection technology has significantly enhanced detection precision and clinical applicability, providing an important support for transfusion safety, managing platelet-related diseases, and developing antiplatelet drugs.
