Study on Zhao Jinxi's Medication Law in Treating Diabetic Kidney Disease Based on Multivariate Data Mining
10.19879/j.cnki.1005-5304.202502034
- VernacularTitle:基于多元数据挖掘的赵进喜治疗糖尿病肾脏病用药规律研究
- Author:
Jiangteng LIU
1
;
Zhichao RUAN
1
;
Yuanyuan LIN
1
;
Xingru PAN
1
;
Ying TANG
1
;
Zhixun GUO
1
;
Jinxi ZHAO
1
Author Information
1. 北京中医药大学东直门医院,北京 100700
- Publication Type:Journal Article
- Keywords:
diabetic kidney disease;
data mining;
Zhao Jinxi;
medication law
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(11):71-76
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the medication law of Professor Zhao Jinxi in the treatment of diabetic kidney disease(DKD).Methods The outpatient prescriptions of Professor Zhao Jinxi from Dongzhimen Hospital of Beijing University of Chinese Medicine in the treatment of DKD were collected from Jan 2021 to May 2024.The Ancient and Modern Medical Case Cloud Platform 2.3.9,Origin 2024,R 4.4.2,SPSS Modeler 18.0,SPSS Statistics 26.0 and Cytoscape 3.10.2 were used to count the frequency,property and taste,meridian tropism,efficacy and dosage of drugs.Association rules,complex networks and clustering analysis were carried out.Results Totally 1 168 prescriptions were included,involving 237 kinds of Chinese materia medica.The high-frequency drugs were Astragali Radix,Salviea Miltiorrhizae Radix et Rhizoma,Dioscoreae Spongiosae Rhizoma,Smilacis Glabrae Rhizoma,etc.The medicinal properties were mostly warm,neutral and cold.The medicinal tastes were mainly bitter,sweet and pungent.They mainly belonged to the liver meridian,spleen meridian and lung meridian.The efficacy was mainly heat-clearing drugs,tonic drugs,and water-clearing and dampness-percolating drugs.18 and 12 drug combinations were obtained by association rules and cluster analysis,respectively.Conclusion Professor Zhao Jinxi's treatment of DKD pays attention to the formation of pathogenesis of"micro abdominal mass",emphasizes"treatment from wind",commonly uses"five methods of kidney treatment"such as tonifying qi,activating blood circulation,dispelling wind,promoting qi and detoxification,and attaches importance to the treatment idea of"three-dimension maintenance kidney",which can provide references for clinical treatment of DKD.
