The research progress of neutrophil extracellular traps in antiphospholipid syndrome
10.3760/cma.j.cn114452-20250303-00123
- VernacularTitle:中性粒细胞胞外诱捕网在抗磷脂综合征中的研究进展
- Author:
Hongyan ZHONG
1
;
Xiaohui CHEN
;
Liyan CUI
Author Information
1. 北京大学第三医院核医学科,北京100191
- Publication Type:Journal Article
- Keywords:
Antiphospholipid syndrome;
Neutrophil extracellular traps;
Thrombosis;
Targeted therapy
- From:
Chinese Journal of Laboratory Medicine
2025;48(6):770-773
- CountryChina
- Language:Chinese
-
Abstract:
Antiphospholipid syndrome (APS) is a systemic autoimmune disease caused by antiphospholipid antibodies. Recent studies have found that neutrophil extracellular traps (NET) play an important role in the pathogenesis of APS. This article mainly introduces the formation, detection and research progress of NET in APS. Additionally, it summarizes the relevant drug targets for APS treatment based on NET, aiming to provide a reference for further research on APS.