Clinical effects of Pinggan Xifeng Huatan Tongluo Decoction on elderly patients with acute cerebral infarction complicated with hypertension
10.3969/j.issn.1001-1528.2025.10.015
- VernacularTitle:平肝熄风化痰通络方对老年脑梗死急性期合并高血压患者的临床疗效
- Author:
Ying-lu JIANG
1
;
Miao-miao ZHANG
;
Tao ZHANG
;
Xue-jun LI
Author Information
1. 皖西卫生职业学院附属医院中医科,安徽六安 237000
- Publication Type:Journal Article
- Keywords:
Pinggan Xifeng Huatan Tongluo Decoction;
conventional treatment;
acute cerebral infarction;
hypertension;
TCM syndromes;
Leptin;
RBP4
- From:
Chinese Traditional Patent Medicine
2025;47(10):3274-3278
- CountryChina
- Language:Chinese
-
Abstract:
AIM To explore the Clinical effects of Pinggan Xifeng Huatan Tongluo Decoction on elderly patients with acute cerebral infarction complicated with hypertension.METHODS Eighty-six patients were randomly assigned into control group(43 cases)for intervention of conventional treatment,and observation group(43 cases)for intervention of both Pinggan Xifeng Huatan Tongluo Decoction and conventional treatment.The changes in clinical effects,TCM symptom effects,TCM symptom score,NIHSS score,FMA score,ambulatory blood pressure indices(SBP,DBP,pulse pressure difference,variation coefficient for systolic blood pressure,variation coefficient for diastolic blood pressure),cerebral hemodynamic indices(PSV,EDV,PI,RI),Leptin,RBP4 and incidence of adverse reactions were detected.RESULTS The observation group demonstrated higher total effective rates of clinic and TCM symptoms than the control group(P＜0.05).After the treatment,the two groups displayed decreased TCM symptom score,NIHSS score,ambulatory blood pressure indices,PSV,EDV,RI,Leptin,RBP4(P＜0.05),and increased FMA score,PI(P＜0.05),especially for the observation group(P＜0.05).No significant difference in incidence of adverse reactions was found between the two groups(P＞0.05).CONCLUSION For the elderly patients with acute cerebral infarction complicated with hypertension,Pinggan Xifeng Huatan Tongluo Decoction can safely and effectively relieve clinical symptoms,enhance anti-hypertensive effect,improve the perfusion of cerebral blood flow,and reduce the levels of serum leptin and RBP4.
