Progress of research on epidemiology and drug resistance mechanism of Elizabethkingia anopheles infection
10.11816/cn.ni.2025-250570
- VernacularTitle:按蚊伊丽莎白菌感染流行病学及耐药机制研究进展
- Author:
Jie SUN
1
;
Yulong ZONG
;
Yongpeng SHANG
;
Shanshan WANG
;
Fangyou YU
Author Information
1. 青岛大学附属泰安市中心医院检验科,山东泰安 271000
- Publication Type:Journal Article
- Keywords:
Elizabethkingia anopheles;
Pathogenic mechanism;
Epidemiology;
Drug resistance mechanism;
Com-bination therapy
- From:
Chinese Journal of Nosocomiology
2025;35(20):3188-3193
- CountryChina
- Language:Chinese
-
Abstract:
In recent years the detection rate of Elizabethkingia anopheles(EA)in China has shown an upward trend,making it one of the important pathogens causing hospital and community infections.EA accounts for 59.3％to 96.2％of the Elizabethkingia species,and can cause meningitis,pneumonia,bacteremia,etc.There are limited researches on its pathogenic mechanism,which mainly involves various virulence factors.EA is a mul-tidrug-resistant bacterium,with drug resistance mechanisms including biofilm formation,efflux pumps and carry-ing multiple resistance genes(such as GOB,BlaB).Currently,minocycline,piperacillin/tazobactam,trime-thoprim/sulfamethoxazole and rifampin are effective drugs for treating EA infections.Clinically,efforts are be-ing made to find the optimal antibacterial drug combination to achieve ideal therapeutic effects.This paper reviews the epidemiological characteristics,pathogenic mechanisms,drug resistance mechanisms and treatment options of EA,aiming to provide a reference for clinical prevention,control,diagnosis and treatment of EA infections.
