Progress of research on Nipah virus infection and alternative drugs
10.11816/cn.ni.2025-250673
- VernacularTitle:尼帕病毒感染及候选药物研究进展
- Author:
Jierong XIN
1
;
Xuejun WANG
;
Shuai DONG
;
Fei WANG
;
Shengqi WANG
;
Shumei WANG
Author Information
1. 广东药科大学药学院,广东 广州 510006;军事医学研究院生物信息中心,北京 100850
- Publication Type:Journal Article
- Keywords:
Nipah virus;
Epidemiology;
Viral life cycle;
Pathogenic mechanism;
Alternative drug
- From:
Chinese Journal of Nosocomiology
2025;35(18):2876-2880
- CountryChina
- Language:Chinese
-
Abstract:
Nipah virus is a highly pathogenic zoonotic virus.The viral characteristics,epidemiological features,viral life cycle and pathogenic mechanisms of Nipah virus were summarized in the article,and the alternative drugs tar-geting various stages of the viral life cycle,including antibody drugs,peptide drugs,and small molecule com-pounds,were systematically reviewed.The current challenges confronting the process of research and development of alternative drugs for Nipah virus were analyzed,and an outlook was also made on future research direction of candidate drugs for Nipah virus,aiming to provide comprehensive and in-depth theoretical reference for prevention and control of Nipah virus as well as the development of drugs and to facilitate the further development of related fields.