Monitoring and cnotrol of bacterial contamination in platelet preprations:exploration of international practices and localization pathways in China
10.11816/cn.ni.2025-250588
- VernacularTitle:血小板制剂细菌污染监测与控制:国际实践与中国本土化路径探索
- Author:
Yang YU
1
;
Yuanyuan LUO
1
Author Information
1. 中国人民解放军总医院第一医学中心输血医学科,北京 100853
- Publication Type:Journal Article
- Keywords:
Bacterial contamination of platelet prepration;
Blood safety;
Monitoring system;
Clinical risk;
Preven-tion and control strategy;
Policy suggestion
- From:
Chinese Journal of Nosocomiology
2025;35(19):2881-2886
- CountryChina
- Language:Chinese
-
Abstract:
Due to specific storage conditions,the relatively high oxygen supply requirements of permeable platelet preprations storage bags and the storage solution that can serve as an additional energy source for some microor-ganisms,platelet transfusions are associated with a significantly higher risk of bacterial contamination compared to other blood components.The transfusion of contaminated platelet preprations can lead to transfusion-transmitted bacterial infections,septicemic reactions and other complications.Therefore,bacterial contamination of platelet preprations poses a serious threat to patients' transfusion safety and has become an urgent issue in the field of transfusion medicine.Monitoring of bacterial contamination in platelet preprations is an effective way to control such contamination.This paper reviews the current epidemiological status,clinical risks and international progress in monitoring bacterial contamination in platelet preprations.It also analyzes the current situation and challenges in China and proposes suggestions tailored to the development of the industry.The aim is to enhance the level of monitoring for bacterial contamination in platelet preprations in China and provide scientific evidence and guidance for ensuring patients' transfusion safety.
